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p.D565A

Homo sapiens (Human)

Functional Impairment

All Features

Entry O75582
gene RPS6KA5
protein name Ribosomal protein S6 kinase alpha-5
organism Homo sapiens (Human)
wt aa D
mut aa A
mutation p.D565A
effect class functional_impairment
protein length 802
wt hydrophobicity -3.5
mut hydrophobicity 1.8
delta hydrophobicity 5.3
wt charge -1.0437
mut charge -0.0392
delta charge 1.0045
wt weight da 133.1027
mut weight da 89.0932
delta weight da -44.0095
wt flexibility 1.068
mut flexibility 0.984
delta flexibility -0.084
wt polarity negative
mut polarity nonpolar
polarity change 1
is charge reversal 0
mutation to proline 0
mutation to glycine 0
mutation to aromatic 0
mutation from aromatic 0
alphafold id AF-O75582-F1
pdb id 1VZO
sasa 35.494
bfactor nan
rna contacts 4a nan
protein contacts 4a nan
proximity to antibiotic site nan
nearest antibiotic nan
plddt 86.19
dist to dc nan
dist to ptc nan
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